• While a large number of clinical

  2019-04-25

  

  While a large number of clinical trials have been completed or underway, there is a lack of strong evidence of their effectiveness and safety. Some experts pointed out that autologous transplantation may put patients at a risk of receiving the genetically defective immune cells, while allogeneic tra

• Time dependent changes in the level

  2019-04-25

  

  Time-dependent changes in the level of anxiety and proportion of patients with anxiety after ICD leukotriene receptor antagonist are unclear. Among patients treated with ICD for the secondary prevention of sudden cardiac death, Kamphuis et al. suggested that the proportion of patients with anxiety d

• Cost effectiveness is another major concern for

  2019-04-25

  

  Cost effectiveness is another major concern for the governments in countries with public health system. Van-den Hout WB et al. at Netherlands [7] did a cost utility analysis showing the cost of radiation treatment including re-treatment for bone metastases using SF versus MF were €2438 versus €3311

• Blebbistatin br Conclusion Our findings may help physicians

  2019-04-25

  

  Conclusion Our findings may help physicians in selecting high-priority patients for bisphosphonate treatment. Zoledronic Blebbistatin is indicated for treating patients with MBD from any malignancy [1,35]; however, many patients do not receive treatment (especially in NSCLC and CRPC). Although i

• Introduction Dilated phase hypertrophic cardiomyopathy

  2019-04-25

  

  Introduction Dilated-phase hypertrophic cardiomyopathy (DHCM) is a rare subset of hypertrophic cardiomyopathy (HCM) [1]. Data available on sustained monomorphic ventricular tachycardia (SMVT) associated with DHCM is scarce. We report a rare case of SMVT caused by a large epicardial scar related to

• It is noteworthy that even with

  2019-04-24

  

  It is noteworthy that, even with low tumor burden in these patients following CR, peak value at CR status is still a useful indicator for OS, both in the whole cohort, and more importantly, in the intermediate-risk subgroup. Slope is mainly determined by tissue vascularization and perfusion, but cap

• br Conclusion br Funding br Conflict

  2019-04-24

  

  Conclusion Funding Conflict of interest Introduction Over the last decade, the unabated increase in the number of transseptal catheterizations has been related to an increase in atrial fibrillation (AF) ablation procedures. Transseptal puncture (TP) is usually safe in experienced hands [

• The great American epidemiologist Bill Silverman taught us

  2019-04-24

  

  The great American epidemiologist Bill Silverman taught us that the road to hell is paved with good intentions. From 1942, during a 12-year period, more than 10 000 infants were blinded through retinopathy of prematurity because paediatricians recommended a minor increase in the concentration of sup

• Although Afnan Holmes and colleagues report covers substanti

  2019-04-24

  

  Although Afnan-Holmes and colleagues\' report covers substantial ground, several issues remain unexamined. For example, why have facility delivery rates in the country stagnated at roughly 50% over the past decade? Although enhancement of women\'s agency in making health-care decisions is necessary,

• Even with the limitations in the available data

  2019-04-24

  

  Even with the limitations in the available data on DALYs, the funding gap is huge. The Research Investments in Global Health study analysed public and philanthropic infectious disease research awards to UK institutions (1997–2013), and compared them to the burden in DALYs, describing a new metric of

• La categorizaci n propuesta por Margaret

  2019-04-24

  

  La categorización propuesta por Margaret Randall es mucho más simple, puesto que distingue tan sólo entre aquellos testimonios en sí de los testimonios para sí. Christina Dupláa analiza tal distinción: Como puede verse, la clasificación es bastante difusa, ya que en la primera categoría se consider

• After the success of the Millennium Development Goals and

  2019-04-23

  

  After the success of the Millennium Development Goals and the reduction in more than 50% of child mortality in children younger than 5 years (Countdown to 2015 report), the survive and thrive motto was given prominence by the Sustainable Development Goals (SDGs). For all children to thrive, we need

• Several true lumen re entry devices have

  2019-04-23

  

  Several true lumen re-entry devices have been introduced into the market, including the Outback catheter, allowing fluoroscopically controlled true arterial lumen re-entry after subintimal guidewire passage. A recent retrospective review reported a successful re-entry rate of 91% in 11 patients with

• Por ltimo una divergencia crucial entre

  2019-04-23

  

  Por último, una divergencia crucial entre los bestiarios y las historias naturales está en la característica glosa alegórica que condujo la lectura moral de la notch signaling en el Bestiario; en la historia natural primó una lectura literal o “histórica” que se finca en la experiencia de los sentid

• Se temos ent o um

  2019-04-23

  

  Se temos, então, um passado eif2a comum e uma gente que “sobreviveu a séculos de genocídio”, parece ser a língua portuguesa e as trocas comerciais direcionadas para os Estados Unidos e para a Europa que nos isolam, como se disséssemos: “Não trabalhamos com pobres como nós”, “Apesar da pobreza, não

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