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Of note cases reported by Britton et al and
2019-04-18
Of note, cases reported by Britton et al. and Keung et al. rely on the demonstration of CD7 and TDT along with myeloid markers to classify the blasts as “biphenotypic” [8,9]. Expression of CD3 is not reported by the authors and these cases would not meet the current 2008 WHO criteria for MPAL. Age
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Two studies are ongoing that promise to
2019-04-18
Two studies are ongoing that promise to be paramount in the prescription of dexamethasone in the prophylaxis of pain flare. NCIC CTG is currently investigating the use of 8mg dexamethasone daily on the day of treatment and four days post-treatment versus placebo of the same duration (NCT01248585) [1
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The canonical or catenin dependent Wnt
2019-04-18
The canonical, or β-catenin dependent, Wnt signaling pathway is critical for the regulation of osteoblast proliferation and survival [95]. Soluble inhibitors of the canonical Wnt pathway such as Dickkopf (DKK1), produced by OBL, and sclerostin, from osteocytes, play important roles in the regulation
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It is noteworthy that in a recent
2019-04-18
It is noteworthy that in a recent study, Le Scouarnec et al. [199]. estimated the burden of rare coding variation in arrhythmia susceptibility genes among 167 BrS index patients and compared that with 167 individuals ≥65 years old with no history of cardiac arrhythmia. The authors concluded that, ex
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br Una pol mica entre traductores Probablemente mientras tra
2019-04-18
Una polémica entre traductores Probablemente, mientras traducía China en armas, Owen leyó y reseñó la traducción de El diablo en el cuerpo de Raymond Radiguet, hecha por Ángel Samblancat. Aun cuando aquél se dedica cyclobenzaprine hydrochloride perorar sobre la vida y la obra de Radiguet, a parti
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Eastern European countries have undergone many
2019-04-18
Eastern European countries have undergone many socioeconomic changes in the past two decades. In particular, in Russia, alcohol was strongly associated with adult mortality. More than half of deaths in Russian men are attributable to cardiovascular disease, with hypertension, hypercholesterolaemia,
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Entre estas perspectivas subyace un complejo concepto de
2019-04-18
Entre estas perspectivas subyace un complejo concepto de paz que implica una relación dialéctica con la justicia, pues ésta “no consiste únicamente en el pacifismo abiraterone acetate ultranza o en la ausencia de guerra”. En ello radica el interés profundo de la tl por la esperanza cristiana de una
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br Conflict of interest br Case presentation A
2019-04-17
Conflict of interest Case presentation A 41-year-old man with a history of palpitations refractory to multiple antiarrhythmic agents for several weeks was referred to our department. A 12-lead electrocardiogram (ECG) demonstrated incessant narrow QRS complex tachycardia (cycle length of 580ms)
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It is well known that the precipitation of
2019-04-17
It is well-known that the precipitation of solid cholesterol monohydrate crystals from supersaturated bile is the first irreversible physical-chemical step in gallstone formation. To study the characteristics, metastable intermediates, and kinetics in the phase transitions of bile, a series of phase
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Vaccines for rotavirus and cholera
2019-04-17
Vaccines for rotavirus and cholera—the two diseases with the highest child mortality rates and a significant fraction of the global diarrhoeal burden—are at preliminary stages of implementation. The use of vaccination as a global primary-prevention strategy can also be rapidly strengthened with the
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br There is growing recognition that children
2019-04-17
There is growing recognition that children bear a substantial burden of tuberculosis morbidity and mortality. However, in regions where the diagnosis is contingent on smear microscopy, the burden attributable to children, who usually have paucibacillary disease, is grossly underestimated. The down
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br Quentin Eichbaum and colleagues describe how new medical
2019-04-17
Quentin Eichbaum and colleagues describe how new medical schools in Africa have developed curricula that include community and rural health components, long-term family attachments, and admission processes that are more equitable for disadvantaged students. All these worthwhile innovations have be
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Una condici n sine qua non es la institucionalizaci
2019-04-17
Una condición sine qua non es la institucionalización de la autonomía de las fuerzas armadas respecto del poder civil, un rasgo específico, del militarismo latinoamericano que ha hecho del Estado de excepción, la norma. En Guatemala, la misma se remonta motilium la Constitución de 1945 y al estatuto
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Las pol ticas cosmopolitas de Or genes
2019-04-17
Las políticas cosmopolitas de Orígenes, por su parte, combinaron los intereses de sus directores, José Lezama Lima y José Rodríguez Feo. El primero, estaba empeñado en la formación de un grupo poético creativo, que trabajara en el diseño de una teleología para el proyecto republicano. Esta teología
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In the case reported by Goldstein et al
2019-04-17
In the case reported by Goldstein et al. [2], a Riata ST lead (St. Jude Medical, Sylmar, CA, USA) was used. The authors did not mention whether the lead was a dual-coil system or not. If the lead was a single-coil system, the possibility of an HV short circuit between the RV coil conductor and the d
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